Chapter 329 - 228: Hooray! The Lead Compound Screening Succeeded

Chapter 329: Chapter 228: Hooray! The Lead Compound Screening Succeeded

The laboratory in the Hepatic Tumor Tower of City First Hospital was officially put into use.

Jia Jun’s team had also come directly from Xiao City to City First Hospital to continue their research.

Thanks to the "Perfect New Drug: Fengmu Tiada (Black)" entry in his mind, Wu Ting already had a pharmaceutical plan formulated. And now that he also possessed the pharmaceutical theory entries from Deng Feifei, Lou Musaang, and Jia Jun, he was completely confident about preparing the new drug’s lead compound.

It was the first day for the hepatic tumor laboratory in Fan City.

The team that had followed Jia Jun from Xiao City was still feeling somewhat disgruntled and unconvinced.

’They’d been brought to Fan City First Hospital under vague circumstances. Could they really develop a new drug here?’

They followed Jia Jun and Lou Musaang because the two genuinely possessed talent and prestige in the R&D field.

’But what were Wu Ting’s credentials?’

’Does a doctor who’s primarily a clinician really understand drug development?’

’Or was it just as most people speculated—that Dr. Wu Ting’s team and project were nothing more than a pipe dream, designed to hype up a concept for investors?’

Many of the original researchers had already quit.

The ones who remained were mostly longtime employees who had followed Dr. Jia and Lou Musaang since graduation. They had come along purely out of trust and support for Jia Jun.

They held no hope of finding a lead compound anytime soon.

Some even figured the team would quietly fall apart and disband after a few more months.

The new drug team’s prospects were a microcosm of the larger Jin Pharmaceutical Group itself.

Plagued by external pressures, morale within the group was low. Many couldn’t take it anymore and had already jumped ship.

As they waited for Wu Ting’s first official meeting, the researchers were all lost in their own thoughts.

While they waited, Wu Ting appeared with Jia Jun and Deng Feifei by his side.

The researchers looked up at the young man.

Wu Ting started by welcoming and encouraging the team, then cut straight to the chase.

"Starting today, we will enter the lead compound screening phase for the new drug Fengmu Tiada..."

"After discussions with Professor Lou and Dr. Jia, for this round of compound screening, we will use molecular modeling technology..."

Wu Ting, who possessed top-tier programming skills, had optimized the Jin Pharmaceutical Group’s original software and designed a proprietary database and screening tool for Wu’s Pharmaceutical Company.

Everyone present was an academic elite, people who knew what they were talking about. As they listened to Wu Ting’s explanation, their eyes lit up. ’Looks like he’s got the goods.’

Wu Ting didn’t want to waste any time either. It was also the first day for the Hepatic Tumor Surgery outpatient clinic, and he had to go see patients shortly.

He went straight into a live demonstration of his new, improved, and optimized screening tool.

"You’re all researchers, so I won’t waste your time with empty words. First, I’ll give you a demonstration of our company’s new tool, the Discovery Studio 3.5-build 3D database... This virtual tool is based on the updated ZINC15 database, designed by the Department of Medicinal Chemistry at the Southern Country Jianing University, Moyin Mountain Branch. This is the largest compound database in the world, used by major drug R&D institutions for virtual screening..."

"This time, we will be using this comprehensive compound database to construct our new drug’s pharmacophore model and perform virtual screening..."

After Wu Ting’s introduction, the researchers had completely settled down and were listening intently.

Even Jia Jun sat quietly to the side, waiting for Wu Ting’s next steps and instructions.

’He’s truly worthy of the high regard President Jin and President Lou have for him. I never expected him to be so brilliant at lead compound screening. No wonder he’s earned the favor and collaboration of so many top international professors.’

’Just securing the complete data from that database is an incredible feat in itself.’

When she thought about the continuous support from the HHMI Research Institute and the backing of influential figures like Deng Fujiu, Ye Xin, and Lin Ning, it wasn’t hard to understand how he could have obtained this foundational database.

This virtual tool would speed up the screening process hundreds of times over!

While Jia Jun was marveling internally, Wu Ting began to display his true capabilities.

"Now, let me introduce you to our experimental setup..."

Wu Ting led the team to the molecular modeling laboratory.

"This is a P20+ tower workstation that President Deng and I had custom-ordered from abroad. The server is equipped with dual Intel Xeon 5218 CPUs, an NVIDIA P5000 compute accelerator card, 256GB of memory, and a brand-new operating system..."

"Besides the top-of-the-line hardware, we will be using a pharmacophore model for our build..."

"This time, we’ll be using the current mainstream method for building our pharmacophore model, which is based on ligand-receptor interactions. We will analyze the interaction between the ’Fengmu Tiada’ fusion polysaccharide protein and PF-06463922 in the 4UXL protein structure to construct a ligand-receptor pharmacophore model. This model will then be used for the subsequent lead compound screening..."

As they listened to Wu Ting’s approach, everything suddenly clicked into place for the team.

Jia Jun, in particular, was growing excited. Wu Ting’s approach was even more perfect than she could have imagined.

Listening to Wu Ting’s design plan and detailed analysis, Jia Jun got the feeling that this young man already had the lead compound figured out. It was as if he were just using her team to go through the motions and officially "screen" it.

’Director Wu is incredible!’

In just over twenty minutes, every researcher on the R&D team was completely won over by Wu Ting’s vision and talent.